Hong Wang | Department of Chemistry

Hong Wang

Professor – Organic & Materials Chemistry; Associate Chair and Graduate Advisor
CHEM 357
Asymmetric Catalysis Through Cooperative Enamine-Metal Lewis Acid Catalysis
Functional Organic Materials Based on p-Extended Porphyrins
Development of Small Molecule Inhibitors Targeting STAT3


  • Ph.D., Organic Chemistry, University of California, Davis, 2003.

Adviser: Kevin M. Smith, LSU Foundation James C. Bolton Distinguished Professor

  • M.S., Inorganic Chemistry, Shandong University, Jinan, China, 1993.
  • B.S., Chemistry, Shandong University, Jinan, China, 1990.

Academic Experience

· Associate Professor, Miami University 2013-2016

· Assistant Professor, Miami University 2007-2013

· Postdoctoral Scholar, The Scripps Research Institute 2005-2007

· Postdoctoral Scholar, Stanford University 2003-2005

Selected Publications

  1. L. Jiang, J. T. Engle, R. A. Zaenglein, A. Matus, C. J. Ziegler, H. Wang,* M. J. Stillman,* "Pentacene-Fused Diporphyrins", Chem. Eur. J. 2014, 20, 1-7. Selected as a "hot paper".
  2. Y. Deng, S. Kumar, H. Wang,* "Merging Organoamino Catalysis with Metal Lewis Acid Catalysis", invited feature article to Chem. Commun., 2014, 4272-4284.
  3. Y. Deng, L. Liu, R. G. Sarkisian, K. Wheeler, H. Wang,* Z. Xu*, "Arylamine-Catalyzed Enamine Formation: Cooperative Catalysis with Arylamines and Acid", Angew. Chem. Int. Ed. 2013, 52, 3663-3667. Highlighted in SYNFACTS, 2013, 9(6), 0631.
  4. L. Jiang, R. A. Zaenglein, J. T. Engle, C. Mittal, C. S. Hartley, C. J. Ziegler, and H. Wang*, "Water-soluble Ionic Benzoporphyrins", Chem Commun, 2012, 6926-6929. Top ten most accessed articles in June 2012 in Chem. Commun. Invited contribution to a themed issue featuring Porphyrins & Phthalocyanines.
  5. Z. Xu, L. Liu, K. Wheeler, H. Wang*, "Asymmetric Inverse-Electron-Demand Hetero-Diels-Alder Reaction of Cyclic Ketones: An Enamine-Metal Lewis Acid Bifunctional Approach", Angew. Chem. Int. Ed, 2011, 50, 3484-3488. Chosen as a "Hot Paper" by the Editors for its importance in a rapidly evolving field of high current interest. Highlighted in SYNFACTS issue 07/11; highlighted in Highlight column on "Organocatalyzed C-C Ring Construction" by Douglass F. Taber.
  6. Liu, Y. Liu, Z. Xu, W. Yu, H. Wang, C. Li, J. Lin,* "A Novel Small Molecule, XZH-5, Inhibits Constitutive and Interleukin-6-Induced STAT3 Phosphorylation in Human Rhabdomyosarcoma Cells", Cancer Science, 2011, 102, 1381-1387. Highlighted in Cancer Science, vol.102, iss.7.
  7. P. Daka, Z. Xu, A. Alexa, H. Wang*, " Primary Amine-Metal Lewis acid Bifunctional Catalysts Based on a Simple Bidentate Ligand: Direct Asymmetric Aldol Reaction", Chem. Commun. 2011, 47, 224-226. Invited contribution to the Issue of Emerging New Investigator. Highlighted in SYNFACT, 04/10, 2011.
  8. R. Deshpande, L. Jiang, G. Schmidt, J. Rakovan, X.-P. Wang, K. Wheeler, H. Wang,* "A Concise Approach to the Synthesis of opp-Dibenzoporphyrins Through the Heck Reaction", Org. Lett. 2009, 4251-4253. Highlighted in SYNFACT, 12/10, 2009.
  9. Z. Xu, P. Daka, H. Wang,* "Primary amine-Metal Lewis Acid Bifunctional Catalysis: the Application to Direct Asymmetric Aldol Reaction", Chem. Commun. 2009, 6825-6827. Highlighted in SYNFACT, 1/10, 2010.
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