My research is focused on making noble metal Nanoparticles dispersed in different biocompatible polymers such as Chitosan, Polyacrylic acid (PAA) and albumin for different biological applications including sensing, antimicrobial/antifungal functions and anticancer effects. Following successful synthesis of pure metal NPs, I will then make mixed metal (of silver and gold) for studies including Cytotoxicity on specific disease models. On this front, my work involves: Investigating Protein corona effect on NP behavior in blood cancer model of lymphoblastic leukemia -: Jurkat clone E6 using. Studies on killing mechanism of AgNP and AgNP-LLL in an in vitro model of malignant brain tumor cells in vitro

This study will also employ Surface Enhanced Raman Spectroscopy technique to study activity of spherical and anisotropic silver NPs, gold NPs and silver/gold bimetallic Nano twins stabilized in biologically benign polymers/proteins such as chitosan, Polyacrylic Acid and different cell culture media prepared in photochemical systems devoid of reducing agents such as CTAB and CTAC. The characteristics of these NPS will then be tested and compared to Nanoparticles prepared through chemical reduction process. We will then investigate the SERS activity of different sizes of the nanoparticles using organic and organometallic dyes including Rodhamine (R6G), Crystal violet (CV) as potential anionic sensors